This philosophy of science book is written by a biomedical scientist for a lay audience but is well-referenced for use by scientific readers and college course curricula. Its thesis is that the current paradigm in the biological and medical sciences, which is responsible for rejecting the existence of a Divine Being, is outdated. There is no factual basis for creating a dichotomy between evolution and Divine Design. Misconceptions about the nature of reality, i.e., the belief that matter is the ultimate cause of everything we think, feel, say, and do, have made it easy to ignore data demonstrating an important biological role for the energetic aspects of matter and to leave the question of the existence of a Divine being to the purview of philosophy and religion. The author uses extensive scientific data to highlight the inconsistencies in current theories and relates her personal journey in trying to explain her observations with purely mechanistic theories. Her ultimate conclusion is that the existence or non-existence of God can no longer be ignored by scientists. It is one of the most important scientific questions there is and like many other issues that were formally relegated to the domain of philosophy, can and should be investigated by modern science.